针刺肝胆经腧穴对偏头痛模型鼠血浆神经降压素和心钠素的影响  

Effects of acupuncture of points of the Liver and Gallbladder Channels on plasma neurotension and atrial natriuretic polypeptide contents in migraine model rats

作　　者：陈昌华[1] 李炜[1] 钟广伟[1] 胡随瑜[1] 石林阶[1] 

机构地区：[1]中南大学湘雅医院中西医结合研究所,长沙410008

出　　处：《中国针灸》2004年第1期63-64,共2页Chinese Acupuncture & Moxibustion

基　　金：湖南省中医管理局科研基金资助 (编号 :982 2 8)

摘　　要：目的 :探讨针刺肝胆经腧穴治疗偏头痛的作用机理。方法 :运用Csillik法复制偏头痛大鼠模型 ,再针刺“太冲”“阳陵泉”穴治疗 ;采用放射免疫 (RIA )法检测偏头痛大鼠血浆神经降压素(NT)和心钠素 (ANP)含量。结果 :模型组大鼠血浆NT含量显著低于正常对照组 (P <0 0 1) ,血浆ANP含量显著高于正常对照组 (P <0 0 1)。针刺治疗后血浆NT和ANP均恢复至正常水平 (P >0 0 5 )。结论 :血浆NT和ANP水平变化可能是偏头痛发病机制中的重要环节之一。针刺可以良性调节血浆NT和ANP的变化。Objective To explore the mechanism of acupuncture of points of the Liver and Gollbladder Channels for treatment of migraine. Methods Migraine model rats were made by Csillik method and treated by acupuncture on “Taichong” (LR 3) and “Yanglingquan” (GB 34); plasma neurotension (NT) and atrial natriuretic polypeptide (ANP) were determined by radioimmunoassay. Results The plasma content of NT in the model group was significantly lower (P<0.01) and the ANP content was significantly higher than that in the normal control group (P<0.01). After acupuncture, the levels of plasma NT and ANP returned to normal levels (P>0.05). Conclusion NT and ANP possibly play an important role in the pathologenesis of migraine, and acupuncture can benignly regulate plasma NT and ANP contents.

关 键 词：肝胆经腧穴 偏头痛 血浆神经降压素 心钠素 针灸疗法 

分 类 号：R246.6[医药卫生—针灸推拿学]