氟西汀、帕罗西汀和氯丙米嗪治疗早泄的临床研究  

Effects of Fluoxetine,Paroxetine and Clomipamine on premature ejaculation:a clinical trial

作　　者：孙成亮[1] 刘继红[1] 王少刚[1] 杨为民[1] 叶章群[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院泌尿外科,武汉430030

出　　处：《临床泌尿外科杂志》2004年第2期91-92,共2页Journal of Clinical Urology

摘　　要：目的 :比较氟西汀、帕罗西汀、氯丙米嗪治疗早泄的疗效和副作用。方法 :分别以口服氟西汀 2 0mg/d、帕罗西汀 2 0mg/d和氯丙米嗪 5 0mg/d治疗早泄 ,疗程 4周 ,通过问卷调查三种药物的疗效及副作用。 结果 :74例患者完成疗程 ,三种药物治疗早泄的有效率氟西汀为 70 .4 %、帕罗西汀为 73.0 %、氯丙米嗪为 76 .1% ,差异无统计学意义 (P >0 .0 5 )。其中氟西汀的副作用发生率较低。结论 :治疗早泄氟西汀能提高患者依从性 。Objective:To evaluate the effect and side effect of Fluoxetine, Paroxetine and Clomipamine on premature ejaculation.Method:After having taken Fluoxetine (20 mg/d), Paroxetine (20 mg/d) and Clomipamine (50 mg/d) for four weeks, the patients were asked to reply the investgating questions about the effect and side effect before and after treament.Result:After four weeks treament, in the 74 cases following our study, there were no significant differences among Fluoxetine, Paroxetine and Clomipamine, but the rate of side effect with Fluoxetine was lower than that with Paroxetine or Clomipamine.Conclusion:Fuloxetin can increase the dependence on the treatment of premature ejaculation and improve indirectly the rate of successful cure.

关 键 词：早泄 药物治疗 抗抑郁药 

分 类 号：R442.9[医药卫生—诊断学]