均匀设计在盾叶薯蓣皂素超临界CO_2萃取中的应用  

The Application of Uniform Design in Supercritical CO_2 Extraction of Dioscorea Zingiberensis C. H. Wright

作　　者：韩凤梅[1] 姚向阳[1] 马晓红[1] 陈勇[1] 

机构地区：[1]湖北大学生命科学学院,湖北武汉430062

出　　处：《化学与生物工程》2003年第5期38-40,共3页Chemistry & Bioengineering

基　　金：湖北省科技厅重大攻关项目:新药研究与开发技术平台(No.2003AA303B02)

摘　　要：采用均匀设计方法,以萃取压力、萃取温度、解析压力、解析温度4因素7水平进行实验,研究了盾叶薯蓣皂素超临界CO_2萃取最佳条件为:萃取压力32 MPa,萃取温度56℃;解析压力8 MPa,解析温度62℃。与传统有机溶剂提取法相比,应用超临界CO_2萃取盾叶薯蓣皂素,不仅方法简便、安全、提取周期短,而且提取的选择性与效率高。This paper studied the best condition to extract diosgenin by the CO_2 supercritical fluid extrac- tion. CO_2 supercritical fluid extraction condition was selected by uniform design ,the extracting pressure, tem- perture, releasing pressure, temperature were the four factors, seven levels of each factor were selected. The best extraction in SFE were extracting pressure 32 MPa,temperature 56℃,releasing pressure 8 MPa, tempera- ture 62℃. The method was simple,selective and efficient,compared with traditional method.

关 键 词：均匀设计 盾叶薯蓣皂素 超临界CO2 萃取 应用 萃取压力 萃取温度 解析压力 解析温度 

分 类 号：TQ28[化学工程—有机化工] TQ028.8