复方安寐口服液治疗失眠的实验研究  

Experimental Study of Curative Effect of Compound Anmei Oral Liquid on Insomnia

作　　者：何建成 浦斌红 刘永琦[3] 李应寿[4] 李永升[4] 

机构地区：[1]龙华医院,上海200032 [2]兰州市城关区人民医院,甘肃兰州730030 [3]甘肃中医学院,甘肃兰州730000 [4]甘肃省中医药研究院,甘肃兰州730000

出　　处：《中成药》2001年第1期48-50,共3页Chinese Traditional Patent Medicine

摘　　要：目的 :本课题旨在研究复方安寐口服液 (FFAM)对实验小鼠自发活动、睡眠、惊厥的影响。方法 :通过测定FFAM对动物活动箱中小鼠自发活动情况 ,观察FFAM对戊巴比妥钠阈剂量、阈下剂量小鼠睡眠时间以及FFAM对硝酸士的宁惊厥的影响来探讨该制剂的作用效果。结果 :研究发现 ,FFAM能抑制小鼠自发活动 ;对小鼠睡眠的影响与戊巴比妥钠有协同作用 ;有对抗硝酸士的宁惊厥发作的作用。且剂量越大 ,作用越明显。结论 :FFAM有明显的镇静、催眠。Objective:To sutdy effects of Compound Anmei Oral Liquid on spontaneous activity, sleep, convulsion of experimental mice.Methods: The effects of oral liquid were observed in the spontaneous activity and the sleep time of mice when they were given Nembuta in a threshold dose or a subliminal dose and its anti convulsant effect to investigate the actions of oral liquid.Results: This oral liquid could inhibit the spontaneous activity and cooperate with pentobarbital sodium to effect the sleep time of mice. It also resist convulsion. Conclusions: Compound Anmei Oral Liquid has obvious sedation, hypnosis and anti convulsant effect.

关 键 词：复方安寐口服液 失眠 

分 类 号：R965[医药卫生—药理学]