小儿肾小球疾病时硒的变化  

CHANGE OF SELENIUM IN CHILDREN WITH GLOME-RULUS DISEASE

作　　者：陈新德[1] 杨献芸 韩子明[1] 杨达胜[1] 张华荣[2] 李守梅 

机构地区：[1]新乡医学院第一附属医院小儿科 [2]新乡医学院第一附属医院耳鼻喉科 [3]新乡医学院第一附属医院中心实验室

出　　处：《新乡医学院学报》1992年第2期103-106,共4页Journal of Xinxiang Medical University

基　　金：省教委资助课题

摘　　要：本文对43例原发性肾小球疾病患儿和24例正常儿童血清和尿硒含量进行了测定,并和血浆蛋白、血红蛋白、血脂、尿蛋白量作相关性检验。结果表明,肾小球疾病患儿与对照组相比血硒明显降低,尿硒明显升高,以急性肾炎组升高最为明显。血硒与血胆固醇和血红蛋白呈正相关,尿硒与血浆球蛋白呈负相关。肾病组尿硒与血胆固醇呈负相关。分析了肾病患者血硒相对高于肾炎患者的原因。The selenium contents in blood and urine of 43 children with glomerulus disease and 24 normal children were measured.The correlative test betwent selenium and hemoglobin, protein,cholesterin in plasma and protein in urine were performed respectively.The results show:compared with normal children,the selenium content in blood of children with glomerulus disease was evidently lower and urinary selenium content was higher,especial- ly in patients with acute glomerulonephritis.Selenium in blood had a positive correlation with cholesterin in plasma and hemoglobin.Urinary selenium had a negative correlation with globulin in plasma.So was the urinary selenium with cholesterin in plasma of patients with nephrotic syndrome.why the selenium in blood of patients with nephrotic syndrome was higher than that of patients with glomeruionephritis was analysed.

关 键 词：硒 肾病综合征 肾小球病 儿童 

分 类 号：R729.926[医药卫生—儿科]