胆红素水平与冠心病发病、血脂水平相关关系的研究  

Study on correlativity of coronary heart disease, lipidemia and serum bilirubin

作　　者：郭牧[1] 周惠萍[1] 刘慧[1] 

机构地区：[1]宁夏银川市第一人民医院,宁夏银川750001

出　　处：《宁夏医学杂志》2004年第1期3-4,共2页Ningxia Medical Journal

摘　　要：目的　就胆红素水平与冠心病 (CHD)发病及血脂水平是否相关进行对照研究。方法　设定CHD组(10 0例 )与对照组 (6 0例 ) ,测定血清总胆红素 (TBIL)、甘油三酯 (TG)、总胆固醇 (CHO)、高密度脂蛋白 (HDL)、低密度脂蛋白胆固醇 (LDL -C) ,采用FRIEDWALD公式计算 (组间比较采用 t检验 )。结果　CHD组TBIL浓度明显低于对照组 (P <0 .0 5 ) ,CHD组TBIL浓度与LDL -C、TG呈一定的负相关。结论　CHD的发生与TBIL的降低有一定的相关性。TBIL具有防止脂质氧化的作用 。Objective To study relations of serum bilirubin level, coronary heart disease(CHD) and lipid level.Methods Serum bilirubin(TBIL),triglycerides(TG),total cholesterol(CHO),high density lipoproteins cholesterol(HDL-C) and of CHD group(100 samples) and low density lipoproteins cholesterol(LDL-C) control group(60 samples) were mensurated.It used for FRIEDWALD formula (analysis with t method).Results The concentration of total bilirubin in CHD group was lower than that in the control group(P<0.05).The concentration of total bilirubin in CHD group shows negative correlativity with concentration of low density lipoproteins cholesterol(LDL-C) and triglycerides (TG).Conclusions Lower serum bilirubin is associated with increased risk for coronary heart disease. Serum bilirubin could prevent lipid from oxygenation, thus avoid the happening of CHD.

关 键 词：冠状动脉心脏病 胆红素 脂蛋白类 

分 类 号：R541.4[医药卫生—心血管疾病]