无创血糖测量的测量界面稳定性研究  

Stability Research of Interface in the Non-invasive Blood Glucose Detection

作　　者：陈文亮[1] 刘蓉[1] 崔厚欣[1] 徐可欣[1] 

机构地区：[1]天津大学精密测试技术及仪器国家重点实验室,天津300072

出　　处：《光电子．激光》2004年第2期242-245,254,共5页Journal of Optoelectronics·Laser

基　　金：国家自然科学基金资助项目(30170261);国家十五科技攻关资助项目(2001BA706B14)

摘　　要：构建了近红外光谱无创血糖测量系统,研究了活体无创血糖测量时测量界面稳定的影响,得出了测头与接触部位刚好完全接触时为最佳接触状态和测头与被测部位接触30s后为最佳测量时间的结论,保证了测量界面的稳定性。实验结果表明,用偏最小二乘(PLS)回归法建立校正集模型,预测均方根误差(RMSEP)分别为0.56mmol/L和0.50mmol/L。The system of non-invasive blood glucose detection by near-infrared spectroscopy was designed,and the influence of interface stability on the measurement was studied.It was determined by experiment that the optimal contact state appears when the probe just contact with the measured position entirely,and the optimal measuring time appears when it is 30 s after the probe contact with the measured position.Experimental results show that under the optimal conditions the root mean square error of prediction(RMSEP) of partial least square(PLS) calibration models are 0.56 mmol/L and 0.50 mmol/L respectively for two oral glucose testers.

关 键 词：近红外光谱 无创血糖测量 测量界面 稳定性 最佳接触状态 最佳测量时间 

分 类 号：R318.51[医药卫生—生物医学工程]