老年股骨颈骨折患者骨代谢改变的观察  

Observation of Variations of Bone Metabolism in Old Patients with Femoral Neck Fracture

作　　者：白孟海[1] 葛宝丰[1] 高梅[1] 陈克明[1] 

机构地区：[1]兰州军区总医院骨科研究所,兰州730050

出　　处：《中国矫形外科杂志》2004年第3期239-240,共2页Orthopedic Journal of China

摘　　要：目的 :股骨颈骨折患者骨代谢指标观察 ,与正常人比较 ,以了解股骨颈骨折与骨质疏松症的关系。方法 :用亲和渗透和全血干化学技术和酶联免疫化学发光法测定 18例股骨颈骨折 (男 8例 ,女 10例 )患者骨源性碱性磷酸酶 (ABLP)和尿脱氧吡啶酚 (DPD)。浓度并与正常人进行比较。结果 :男、女组股骨颈骨折患者骨源性碱性磷酸酶分别为 ( 183 .3 3 +-2 3 .0 0 )和 ( 188.89+-3 5 .3 3 ) ,尿DPD分别为 ( 2 81.11+-84.15 )和 ( 2 94.3 1+-76.94)。男女股骨颈骨折组BALP和DPD水平与对照组比较有显著差异 (P <0 .0 5 ) ,DPD浓度男女观察组与对照组比较均有非常显著差异 (P <0 .0 1)。结论 :老年人股骨颈骨折发生与骨质丢失有一定的关系 ,提示预防老年人股骨颈骨折首先预防骨质疏松症的发生。Objective: To observe bone metabolism indexes changes in patients with femoral neck fracture and compare it with that of normal persons and study the relations between femoral neck fracture and osteoporosis. Methods: Bone alkaline phosphates(BALP) and DPD were assayed by chemical technique? ELISA in 18 patients with femoral neck fracture (8 males, 10 females), concentration was compared with that of normal persons. Results: BALP in males and females with femoral neck fracture were (183.33+-23.00) and (188.89+-35.33) respectively, urine DPD were (281.11+-84.15) and (294.31+-76.94) respectively. The levels of BALP and DPD in males and females with femoral neck fracture had significant differences with that of control group ( P <0.05),the concentration of DPD in observing group had significant differences with the control group ( P < 0.01 ). Conclusions: The incidence of femoral neck fracture in old patients is related to bone loss, the results suggest that the prevention of osteoporosis is the critical step for prevention of femoral neck fracture in elderly people.

关 键 词：老年人 股骨颈骨折 骨源性碱性磷酸酶 尿脱氧吡啶酚 骨代谢 骨质疏松症 骨质丢失 

分 类 号：R683.42[医药卫生—骨科学] R336[医药卫生—外科学]