3,5-二氨基苯甲酸-4′-联苯酯的合成  

Synthesis of 3,5-Diaminobenzonic-4′-diphenyl Ester

作　　者：杨进[1] 刘习奎[1] 汤嘉陵[1] 顾宜[1] 

机构地区：[1]四川大学高分子科学与工程学院高分子材料工程国家重点实验室,四川成都610065

出　　处：《四川大学学报（工程科学版）》2004年第1期53-56,共4页Journal of Sichuan University (Engineering Science Edition)

基　　金：国家科技部"十五"863资助项目(2001AA334020)

摘　　要：为了提高由含联苯酯侧基的二硝基化合物还原制备相应二元胺的产率,对在水合肼、氯化亚锡及催化加氢3种不同还原体系中合成3,5-二氨基苯甲酸-4′-联苯酯的方法进行对比研究,用红外光谱和核磁共振氢谱对产物进行结构表征,并探讨了最佳反应条件。研究结果表明:以C-Pd为催化剂的催化加氢还原体系合成产物效果最佳,其产率高,后处理简便,反应的最佳条件为:C-Pd用量5%,50℃,反应时间为10h。In order to increase the yield of diamine, which was synthesized by the reduction of corresponding dinitro-compound containing biphenyl ester groups, 3,5-diaminobenzoic-4'-diphenyl ester was synthesized using three different reduction systems: hydrazine hydrate, stannous chloride and catalytic hydrogenation. The product was characterized by FTIR and 1H-NMR. The results showed that the product obtained in the catalytic hydrogenation system with Pd/C catalyzer has better effect, higher yield and the purification method is more convenient. The optimum condition was 5% Pd/C dosage, 50°C, 10 h.

关 键 词：3 5-二氨基苯甲酸-4′-联苯酯 合成 催化加氢 硝基还原 反应条件 

分 类 号：O625.523[理学—有机化学]