辐照到培皿中细胞单层上的毫米波功率流密度分析  

Power Density Analysis on Millimeter Waves Irradiated into Cell Monolayers in Culture Dishes

作　　者：赵建勋[1] 牛中奇[1] 鲁德强[2] 

机构地区：[1]西安电子科技大学电子工程学院,西安710071 [2]浙江大学医学院微波研究室,杭州310031

出　　处：《生物医学工程学杂志》2004年第1期97-101,共5页Journal of Biomedical Engineering

摘　　要：涉及到细胞层次上的毫米波生物学效应的实验使用了内含细胞单层的培皿 ,并使毫米波从下方进行辐照。针对培皿直径远大于毫米波波长的情况 ,分析了辐照到细胞单层上的毫米波功率流密度与培皿厚度、毫米波波长以及培皿和培养液的电磁参数等影响因素的关系 ;使用电磁场时域有限差分法分析了一种典型的直径与波长相近的小口径培皿的结构对辐照到细胞单层上的毫米波功率流密度的影响。结果表明此类实验需要对辐照到细胞单层上的毫米波功率流密度进行严格分析、精确测量和准确计算 。Biological effects of millimeter waves (MMWs) at the cellular level are explored in experiments using culture dishes containing cell monolayers with MMW irradiated from the underneath. Analysis is carried out for culture dishes with diameters much larger than the MMW wavelength to discover the relation between the portion of the incident MMW power density (PD) irradiated into the cell monolayer and the interfering factors such as the bottom thickness of the culture dish, the MMW wavelength, and the electromagnetic parameters of the dish and culture solution. With the help of the finite-difference time-domain (FDTD) technique, another analysis is performed to display the effect of the dish geometries upon the MMW PD irradiated into the cell monolayer in a specific culture dish with a diameter similar to the MMW wavelength. The results indicate that rigorous analysis, precise measurement and accurate calculation of MMW PD are essential accompaniments for these experiments, and large-diameter culture dishes are more preferred in experiments to small-caliber ones.

关 键 词：培皿 细胞单层 毫米波辐照 功率流密度 生物学效应 

分 类 号：R312[医药卫生—基础医学]