可降解、可吸收性骨科材料类型及发展  

Development of Biodegradable and Bioabsorbable Bone-repaired Materials

作　　者：葛建华[1] 王迎军[1] 贾德民[1] 

机构地区：[1]华南理工大学,材料学院,广州,510640

出　　处：《生物医学工程学杂志》2004年第1期151-155,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金重点项目资助 ( 5 993 2 0 5 0 );广东省自然科学基金项目资助 ( 990 62 1);广东省重点科技攻关项目资助( A3 0 2 0 2 0 2 0 2 )

摘　　要：综述了可用作可降解、可吸收性骨科材料的高分子材料、无机材料和复合材料 ,主要对聚乳酸、甲壳素和磷酸三钙等可降解吸收骨科材料的性质、用途等做了较为详细的阐述。并对可降解吸收骨科材料的发展趋势进行了探讨。认为各种材料之间的复合 ,特别是与骨形态发生蛋白以及骨髓基质干细胞之间的复合 ;现有材料的增强 ;This paper reviews recent work on biodegradable and bioabsorbable materials, including macromolecular, inorganic, and compound materials which have been used as bone-repaired devices. The properties and uses of poly(lactic acid), chitin and tricalcium phosphate are expounded. At the same time, we discuss the trend in the development of biodegradable and bioabsorbable bone-repaired materials. In our opinion , the development of biodegradable and bioabsorbable bone-repaired materials forcuses on the composite of different materials, especially the composite of BMP and MSCs; on the improvement of the mechanical properties of materials; and on the search for new suitable materials.

关 键 词：骨科材料 骨髓基质 干细胞 甲壳素 聚酯 

分 类 号：R318.08[医药卫生—生物医学工程]