不同蚯蚓纤溶酶组分纤溶活性的相互作用  

Interaction in Fibrinolytic Activities of Different Components of Earthworm Fibrinolytic Enzymes

作　　者：刘美艳[1] 张双全[2] 张健[1] 

机构地区：[1]徐州师范大学生物系,江苏徐州221116 [2]南京师范大学生命科学学院生物化学与分子生物学研究室,江苏南京210097

出　　处：《药物生物技术》2004年第1期42-44,共3页Pharmaceutical Biotechnology

摘　　要：采用纤维蛋白平板法对从赤子爱胜蚓中纯化的 4种纤溶酶 (EFE 1,EFE 2 ,EFE 3,EFE 4 )组分的单独作用及相互作用的活性进行了研究 ,结果表明 ,4种组分单独作用时以EFE 4的活性最强 ,其次是EFE 3,最弱的是EFE 1和EFE 2。 4种组分之间存在着相互作用 ,其纤溶活性的大小因组合不同而不同 ,不同组分联合使用时 ,以EFE 2 4的活性最强 ,除EFE 1 3、EFE 3 4两组合的活性与其单独作用的活性差异不显著外 。Fibrinolytic activitiy of separate component and interaction activities of components of earthworm fibrinolytic enzymes (EFE-1,EFE-2,EFE-3,EFE-4) were studied on fibrin plate. The results showed that fibrinolytic activitiy of EFE-4 was the strongest in separate component treatment,the second was EFE-3,EFE-1and EFE-2 were all the weakest. Interaction activities of four components of EFE was different according to different combinations. In all combinations, fibrinolytic activitiy of EFE-2-4 was the strongest. The interaction activities of components was significantly stronger than separate component except EFE-1-3、EFE-3-4.

关 键 词：蚯蚓纤溶酶 纤溶活性 相互作用 

分 类 号：Q556[生物学—生物化学]