冠心病患者心律失常的昼夜节律研究  

Circadian rhythm of arrhymias in coronary heart disease

作　　者：王秀[1] 贺常萍[2] 王慧[2] 

机构地区：[1]皖南医学院中西医结合研究中心,安徽芜湖241001 [2]皖南医学院第二附属医院心内科

出　　处：《皖南医学院学报》2004年第1期59-60,78,共3页Journal of Wannan Medical College

摘　　要：目的　探讨冠心病患者不同心律失常的昼夜节律。方法　采用回顾性调查方法进行研究。结果　①房性心律失常整体呈双峰双谷型昼夜节律变化。房性早搏在申酉时为发作之低谷 ,房性心动过速在卯至午时为发作高峰 ,二者之间经统计学分析差异无显著性 (P >0 .2 5 )。②室性心律失常白昼发作呈W型曲线 ,在午时为高峰。室性早搏卯时至酉时发作为主 ,室性心动过速集中于午、申两个时段发作 ,呈M型趋势。二者经统计学处理差异具有显著性 (P <0 .0 1)。③房性心律失常与室性心律失常的昼夜节律变化差异也具有非常显著性 (P <0 .0 1)。结论　冠心病不同心律失常的昼夜节律不同 ,临床可根据其昼夜节律对其进行治疗 ,从而预防冠心病的发作或加重 ,降低心脏性猝死率。Objective To explore the circadian rhythm of different arrhymias in coronary heart disease.Methods Retrospective research was used.Results\ ①The whole rhythm of atrial arrhymias showed double peak type. Atrial extrasystole got to its lowest value at Shen and You (15:00～19:00),atrial tachycardia got to its peak from Mao to Wu (5:00～13:00).②Ventricular arrhymia got to its peak at Wu(11:00～13:00),with the rhythm curve like the letter “W”.The rhythm of ventricular extrasystole showed W type.Ventricular tachycardia came down with the illness at Wu(11:00～13:00) and Shen(15:00～17:00).The rhythm of two ventricular arrhymias were different(P<0.01).③The circadian rhythm was different between atrial arrhymias and ventricular arrhymias(P<0.01).Coclusion\ The circadian rhythm of different arrhymias in coronary heart disease is different.It is suggested that circadian rhythm should be considered in clinical treatment to prevent onset or development of coronary heart disease.

关 键 词：冠心病 心律失常 昼夜节律 心脏性猝死 动态心电图 

分 类 号：R541.4[医药卫生—心血管疾病]