保肾口服液影响IgA肾病小鼠T细胞增殖及分泌IL-2的实验研究  

The Experimental studies of the Protecting Kidney Oral Liquid Affecting the T-cell Proliferation and Secretion IL-2 in IgA Nephrotic mice

作　　者：陈玉春[1] 阮诗玮[2] 王碧英[1] 王伟[2] 

机构地区：[1]福建省中医药研究院,福建福州350003 [2]福建中医学院附属人民医院,福建福州350004

出　　处：《福建中医学院学报》2004年第1期17-19,60,共4页Journal of Fujian College of Traditional Chinese Medicine

基　　金：福建省中医药重点资助课题 ( No.0 70 2 )

摘　　要：观察保肾口服液对 Ig A肾病小鼠 T细胞 3H-Td R掺入及其分泌 IL-2水平的影响 ,结果表明低、中、高 3种浓度的保肾口服液均能显著促进 Ig A肾病小鼠的自发性和 Con A刺激的 T细胞 3H-Td R掺入 ,促进 T细胞合成 ,分泌 IL-2 ,提前给药作用相同。提示保肾口服液有显著增强 IgTo observe the influence which the Protecting Kidney Oral Liquid exerts to the level on T cell H TdR incorporation and secreting IL 2 of suffering IgA nephrophy mice.The results showed that the Oral Liquid whether it is the high,middle or low concentration of the three species,can notably facilitate the idiophathetic and ConA inciting T cell incorporation of the IgA nephrotic mice,facilitate the T cell proliferation and secretion of IL 2.Giving drug in advance,the action is identical.It showed that the function of the Protecting Kidney Oral Liquid that can significantly enhance the cellular immunocompetence of the IgA nephrotic mice.

关 键 词：保肾口服液 IGA肾病 小鼠 T细胞 细胞增殖 IL-2 细胞免疫功能 药理作用 

分 类 号：R285.5[医药卫生—中药学] R277.526[医药卫生—中医学]