自然流产患者血清瘦素水平的研究  

Investigation of serum leptin levels in women suffering spontaneous abortion

作　　者：刘春晖[1] 高云荷[1] 

机构地区：[1]兰州医学院第二附属医院妇产科,兰州730030

出　　处：《中国优生与遗传杂志》2004年第1期78-79,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的　探讨孕早期母体血清瘦素水平与自然流产的关系及其临床意义。方法　用放射免疫法测血清瘦素、胰岛素水平 ,并测量身高、体重 ,计算体重指数。结果　自然流产患者血清瘦素水平平均为 5 .2 5± 1.2 0ng/ml,正常妊娠者为 9.15± 1.96ng/ml,两组比较差异有显著性。血清瘦素水平与体重指数、胰岛素呈正相关。两组胰岛素水平差异无显著性。结论　自然流产患者血清瘦素水平明显降低 ,低瘦素水平是自然流产发生的原因之一。Ojective: To investigate if maternal serum leptin levels in the frist trimester of pregnancy were associated with spontaneous abortion and its clinic significance. Methods: Serum leptin levels were measured by radioimmunoassay using commercial kites . Height and weight was measured and BMI calculated. Results: Serum leptin levels were 5.25±1.20ng/ml in spontaneous abortion pregnancy, 9.15±1.96ng/ml in normal pregnancy, significant differences were found between the two groups. The serum leptin levels in all women were positively correlated with their BMI and serum insulin levels. There were no significant differences between the two groups in serum insulin levels. Conclusion: The serum leptin levels were significantly lower in spontaneous abortion pregnangcy compared with normal pregnancy, low serum leptin levels may be one of the reasons of spontaneous abortion.

关 键 词：自然流产 瘦素 胰岛素 

分 类 号：R714.21[医药卫生—妇产科学]