生长抑素治疗顽固性腹泻 37例临床观察(英文)  

Clinical observation on somatostatin treatment in 37 patients with intractable diarrhea

作　　者：李楠[1] 周建飞[1] 朱超慧[1] 莫显刚[1] 陈昕[1] 

机构地区：[1]解放军309医院消化科,北京100091

出　　处：《中国现代医学杂志》2004年第3期38-40,44,共4页China Journal of Modern Medicine

摘　　要：目的　总结在常规治疗无效的各型顽固性腹泻使用善宁治疗的疗效。方法　 1999年以来各型顽固性腹泻 37例 ,善宁 30 0 μg/d～ 12 0 0 μg/d ,观察临床症状、腹泻次数、住院时间等。 结果　善宁治疗后临床症状在 2d内消失的占 3/ 4 ,腹泻明显减少 ,显效加有效的为 75 .7% ,明显改善全身症状。结论　善宁能抑制肠液分泌 ,减少蠕动 ,对各型顽固性腹泻有明显的治疗作用 ,临床上需进一步总结其疗效。Objective:To summarize the therapeutic effect of somatostatin on intractable diarrhea. Methods: Since 1999,37 patients with intractable diarrhea were treated by somatostatin 300 μg～1 200 μg per day for 1～12 days.Clinical condition,number of diarrhea,side effects and so on were observed. Results:About three fourths of the patients were resumed within 2 days,the rate of efficacy was 75.7%.Conclusions:Somatostatin may control intestinal fluid excretion and decrease intestinal peristalsis. It's an effective drug to treat intractable diarrhea. We must further take clinical data.

关 键 词：生长抑素 顽固性腹泻 

分 类 号：R512.5[医药卫生—内科学]