Radiolabeling of N-Succinimidyl-3-[(125)~I]iodobenzoate intermediate  

作　　者：WANGLi-Hua WANGYong-Xian YINDuan-Zhi LIJun-Ling 

机构地区：[1]ShanghaiInstituteofAppliedPhysics,theChineseAcademyofSciences,Shanghai201800

出　　处：《Nuclear Science and Techniques》2004年第1期43-45,共3页核技术（英文）

摘　　要：Organostannanes were important precursors which was easy to radioiodinate. N-Succinimidyl-3- (tri-n-butylstannyl) benzoate (STB) was radiolabeled using Iodogen to get radioactive N-Succinimidyl-3-iodobenzo- ate (S125IB) with 96% of high radiochemical yield. The optimization of labeling condition was explored in this study. S125IB was stable at room temperature in dark. Cold SIB was prepared as a standard and IR and NMR results were given in this article.Organostannanes were important precursors which was easy to radioiodinate. N-Succinimidyl-3- (tri-n-butylstannyl) benzoate (STB) was radiolabeled using Iodogen to get radioactive N-Succinimidyl-3-iodobenzo- ate (S125IB) with 96% of high radiochemical yield. The optimization of labeling condition was explored in this study. S125IB was stable at room temperature in dark. Cold SIB was prepared as a standard and IR and NMR results were given in this article.

关 键 词：放射性同位素示踪 STB 稳定性 放射化学 

分 类 号：O657.4[理学—分析化学]