利用掺杂及梯度复合技术对生物材料进行TiO_2(Ta^(5+))/TiN薄膜表面改性的研究  

Surface modification of TiO_2(Ta^(5+))/TiN film forbiomaterials using doping and duplex technology

作　　者：陈俊英[1] 冷永祥[1] 杨萍[1] 孙鸿[1] 王进[1] 万国江[1] 黄楠[1] 

机构地区：[1]西南交通大学材料工程系,四川成都610031

出　　处：《材料科学与工艺》2004年第1期64-66,共3页Materials Science and Technology

基　　金：国家自然科学基金资助项目(39770212;39870199和30300087);国家重点基础研究发展规划资助项目(G1999064706).

摘　　要：采用磁控溅射技术同热氧化相结合的方法合成TiO2(Ta5+)/TiN复合薄膜,并对薄膜的硬度、摩擦磨损等力学特性以及血小板粘附等血液相容性进行了研究.研究结果表明,掺杂使血液相容性提高,梯度复合使力学特性改善,因而薄膜具有良好的力学耐久性和血液相容性.此外,薄膜与血液的界面张力也被测试.结果表明,低的薄膜/血液界面张力改善了TiO2(Ta5+)/TiN复合薄膜的血液相容性.In order to investigate the hemocompatibility and mechanical property of Ta^(5+) doped TiO_2/TiN films, TiO_2/TiN film contained different Ta density were synthesized using JR4-4B type magnetron sputtering deposition system and heat oxidation methods. The thickness of the film is 1.2μm. The micro-hardness and wear resistance of films were examined. In vitro platelet adhesion investigation was used to evaluate the blood compatibility of films. It was found that the mechanical properties were improved because of duplex technology of TiO_2/TiN. The result of vitro platelet adhesion show that the number of platelets adherent on the TiO_2 (Ta^(5+))/TiN film surface is much less than that on low temperature isotropic pyrolytic carbon (LTIC) surface. It is believed that the existence of Ta^(5+) benefits the blood compatibility. The blood/TiO_2 (Ta^(5+))/TiN film surface interfacial tension γ_(s·blood)={(γ~p_(blood))^(1/2)-(γ~p_s)^(1/2)}~2+{(γ~d_(blood))^(1/2)-(γ~d_s)^(1/2)}~2value is 0.838 N/m and lower than that of LTIC. The relationship between the surface tension and blood compatibility is discussed in this paper. The TiO_2 (Ta^(5+))/TiN film maybe is one of the coating for modification of artificial organ.

关 键 词：梯度复合 磁控溅射 生物材料 TiO2(Ta^5+)/TiN复合薄膜 表面改性 血液相容性 力学特性 掺杂技术 

分 类 号：R318.08[医药卫生—生物医学工程]