番荔枝化学成分研究  

STUDIES ON THE CHEMICAL CONSTITUENTS OF ANNONA SQUAMOSA

作　　者：杨小江[1] 徐丽珍[1] 孙南君[1] 王树春 郑启泰[3] 

机构地区：[1]中国医学科学院药用植物资源开发研究所 [2]陕西卫生干部学院,西安710068 [3]中国医学科学院药物研究所,北京100050

出　　处：《药学学报》1992年第3期185-190,共6页Acta Pharmaceutica Sinica

摘　　要：从番荔枝(Annona squamosa)中分离得到12个化合物,分别鉴定为liriodenine(AS—1),穆坪马兜铃酰胺(moupinamide,AS-2),-(-)-kauran-16α-01-19-oic acid(AS-3),16β,17-dihydroxy-(-)-kauran-19-oic acid(AS-4),anonaine(AS-5),16α,17-dihydroxy-(-)-kauran-19-oic acid(AS-6),(-)-isokaur-15(16)-en-17,19-dioic acid(AS-7),番荔枝酰胺squamosamide(AS-8),16α-methoxy-(-)kauran-19-oicacid(AS-9),sachanoic acid(AS-10),(-)-kauran-19-al-17-oic acid(AS-11),daucosterol(AS-12)。其中,番荔枝酰胺(AS-8)是新化合物,AS-9是第一次从植物中得到的天然产物。Twelve compounds were isolated from Annona squamosa. Their struc-tures were identified as liriodenine ( AS-1), moupinamide (AS-2), -(-) -kauran-16α- ol -19 - oic acid(AS-3), 16β,17 - dihydroxy - (-) - kauran- 19 - oic acid(AS-4), anonaine (AS-5), 16α,17- dihydroxy- (-) - kauran - 19 - oic acid (AS - 6),(-)-isokaur- 15(16)-en- 17, 19-dioic acid(AS-7), squamosamide(AS-8), 16α- mcthoxy- ( - ) . kauran- 19- oic acid( AS-9 ), sachanoic acid(AS- 10 ), ( - )- kauran- 19-al- 17-oic acid(AS-11), daucosterol(As-12). Among them, AS-8is a new amide, AS- 9 is a new natural product.

关 键 词：番荔枝 番荔枝酰胺 化学成分 

分 类 号：R282.710.3[医药卫生—中药学]