O,O′-二烷基-O″-(5-取代-3-苯并噻吩乙腈肟)磷酸酯及硫代磷酸酯的合成  

SYNTHESIS OF O,O′-DIALKYL-O″-(5-SUBSTITUTED-3-BENZOTHIENGLYOXYLONITRILE OXIMINO)PHOSPHATES AND THIOPHOSPHATES

作　　者：王浦海[1] 张立康[1] 王锐[1] 尹忠 吴秀琴[1] 

机构地区：[1]南京药物研究所,南京210009

出　　处：《药学学报》1992年第7期510-514,共5页Acta Pharmaceutica Sinica

摘　　要：合成了18个O,O′-二烷基-O″-(5-取代-3-苯并噻吩乙腈肟)磷酸酯及硫代磷酸酯类化合物(Ⅰ_(1～18))。初步杀螺试验结果表明,其中5个化合物,即Ⅰ_(2,3,7,11,12)有明显的杀螺增效作用。In order to search for potential molluscicidal synergists, eighteen O,O′-dialkyl-O″-(5-substituted-3-benzothienglyoxylonitrile oximino) phosphates andthiophosphates were synthesized. Preliminary biological screening showed that compoundsI_(2,3,7,11,12) combined with sodium pentachlorophenate exhibited significant molluscicidalsynergism against snails (Oncomelanis hupensis).

关 键 词：磷酸酯 硫代磷酸酯 杀螺剂 

分 类 号：R979.8[医药卫生—药品]