逍遥丸的三维高效液相色谱法鉴定和指标成分的定量  

THE IDENTIFICATION AND DETERMINATION OF MARKER SUBSTANCES IN XIAOYAO WAN BY THREE DIMENSIONAL HPLC

作　　者：陈发奎[1] 孟宪纾[1] 郭允珍[1] 鹿野美弘[2] 

机构地区：[1]沈阳药学院,沈阳110015 [2]北海道药科大学

出　　处：《药学学报》1992年第11期853-857,共5页Acta Pharmaceutica Sinica

摘　　要：用三维高效液相色谱(three dimensional HPLC)法对中成药逍遥丸进行了分析。结果表明该法用于逍遥丸中单味中药鉴定及其指标成分(marker substances)含量测定均得到满意结果。A Chinese traditional patent medicine Xiaoyao Wan was analysed by three dimensinal HPLC. The result shows that the Chinese traditional medicines involved in Xiaoyao Wan were identified excellently and the content of marker substances can be determined accurately. According to the results of determination, the content of saikosaponin b_1, b_2, glycyrrhizin, paeoniflorin and atractylenolide Ⅲ in Xiaoyao Wan was 0. 43, 0. 53, 5. 22, 3. 95 and 0. 16 (mg/g), respectively); The RSD was 1.2, 0. 8, 0. 4, 0. 3 and 1.0 (%) respectively.

关 键 词：逍遥丸 中成药 分析 高效液相色谱 

分 类 号：R286.0[医药卫生—中药学]