系统性红斑狼疮住院人群临床流行病学调查分析  

The Clinical Epidemiologic Studies on In-patients with Systemic Lupus Erythmatosus

作　　者：李结华[1] 叶冬青[2] 胡以松[2] 杨世贵[2] 徐元勇[2] 

机构地区：[1]安徽医科大学附属医院干部病房,合肥230022 [2]安徽医科大学公共卫生学院流行病学与卫生统计系

出　　处：《中国预防医学杂志》2004年第1期13-15,共3页Chinese Preventive Medicine

基　　金：安徽省自然科学基金资助项目 (984372 31 ) ;安徽省教育厅重点科研计划基金资助项目 (2 0 0 0kj1 75ZD)

摘　　要：目的　探讨系统性红斑狼疮 (SLE)患者发病特点及诊疗情况 ,有助于临床医师进一步加强对SLE的认识。方法　用EPIInfo软件建立数据库 ,分析 1990年 1月至 2 0 0 1年 6月 690例安徽医科大学第一附属医院SLE住院患者的病案资料。结果　①近 5年SLE患者住院人数有所下降。②发病特点 :SLE患者高峰年龄在 2 0～ 40岁 ,以农民最多 ;女性多于男性 ,男女性别比为 1∶7 73 ,但 40岁以后两性差别显著缩小。感染仍为SLE患者的常见诱因 ,但有 1/3患者发病与妊娠有关 ;在转科的SLE患者中肝损害为首发症状者最多。③诊疗情况 :治疗结果以好转为主 ;影响转科因素有住院天数、入院时情况、病程和治疗结果。结论　①SLE住院人数近年有下降趋势 ,SLE住院人数难以代表大规模流行病学调查。各级医务人员要关注SLE的高峰年龄和相对危险人群。②SLE目前基本不能根治。对于以消化系统、循环系统或神经系统为首发症状的患者也应考虑到本病的可能。Objective To study the clinical characteristic of systemic lupus erythmatosus(SLE)and circumstances of the diagnosis and treatment in patients with SLE. Methods With EPI Info software,database is created.The record data of 690 in-patients with SLE was analyzed from January,1990 to June,2001,in First Affiliated Hospital of Anhu Medical University. Results (1)The number of in-patients with SLE had decreased during the past five years.(2)The peak age of patients with SLE was from 20 to 40 year-old.The most patients were peasants.The number of female patients was more than that of male patients.The ratio of women to men was 1∶7.73.But the gender difference was significantly reduced among patients more than 40 year-old.Infection was still the most cmmon cause of SLE and 1/3 patients were related with gestation.The first symptom of most transfer patients was disorder of liver function.(3)The main treatment result was relievable.The influential factors for transfer were length of hospital stay,the situation of being admmitted to hospital,the course of disease and the result of treatment. Conclusions (1)The number of in-patients with SLE had decreased recently.But it is difficult to substitute the large-scare epidemiological investigation.The peak age and patients suffering easily from SLE should be concerned by medical personnel at all levels.(2)At present,there was no effective radical treatment.Those patients whose first symptom was caused by digestive,cardiovascular and nervous system disorder had the possibility of suffering SLE.

关 键 词：系统性红斑狼疮 住院人群 SLE 流行病学 诊断 治疗 

分 类 号：R593.241[医药卫生—内科学] R18[医药卫生—临床医学]