自体微粒皮移植术在大面积深度烧伤MODS防治中应用  

Prevention and treatment of MODS with micro-skin autograft for extensively deep burns

作　　者：胡德林[1] 方林森[1] 王永杰[1] 余又新[1] 汪昌荣[1] 

机构地区：[1]安徽医科大学第一附属医院烧伤科,合肥230022

出　　处：《安徽医科大学学报》2004年第1期56-58,共3页Acta Universitatis Medicinalis Anhui

基　　金：安徽省卫生厅重点学科资金资助

摘　　要：目的　探讨自体微粒皮移植术对大面积深度烧伤多器官功能障碍综合征 (MODS)发生的影响。方法　分析性研究收治的大面积深度烧伤患者 6 4例 ,根据早期创面处理方法的不同分为切痂自体微粒皮移植术组和切痂邮票状植皮术组 ,两组患者的一般情况具有可比性 ,自体微粒皮移植术组行一次性大面积切痂自体微粒皮和大张异体皮联合移植术 ,切痂邮票状植皮术组分次行部分Ⅲ度创面切痂自体邮票状皮片移植术 ,比较两组患者脓毒症和MODS的发生率。结果　自体微粒皮移植术组脓毒症和MODS的发生率分别为 34 4 %和 18 8% ,明显低于切痂邮票植皮术组的 6 2 5 %和 4 3 8% ,差异有显著性 (P <0 0 5 )。Objective To investigate the effects of micro-skin autograft on MODS in extensively deep burns. Methods 64 patients with extensively deep burns were retrospectively analyzed. The patients came from our department from 1993 to 2002 and were divided into two groups:the group treated with micro-skin autograft after extensive eschar excision in one operation and the group treated with stamp skin-grafting after routine repeated escharectomy. The incidence of sepsis and MODS were compared between the two groups. Results The incidence of sepsis and MODS was 34.4% and 18.8% respectively in indicating a significant difference between the two groups ( P <0.05). Conclusion Micro-skin autograft after extensive eschar excision in one operation can reduce the incidence of MODS in extensively deep burns.

关 键 词：自体微粒皮移植术 大面积深度烧伤 MODS 预防 治疗 并发症 多器官功能障碍综合征 

分 类 号：R644[医药卫生—外科学] R622.1[医药卫生—临床医学]