火麻仁油对复方地芬诺脂致便秘模型小鼠血清及脑NO及胸腺组织学的影响  

The Effect of Oil of Fructus Cannabis on the Sera, Brains’ NO and Thymus Histology of the Mice in Constipation Caused by Compound Di Fen Nuo Zhi

作　　者：曹俊岭[1] 陈刚正[2] 任汉阳[1] 张瑜[1] 薛春苗[1] 

机构地区：[1]河南中医学院 [2]河南省平顶山市第一人民医院

出　　处：《河南中医学院学报》2004年第1期25-26,共2页Journal of Henan University of Chinese Medicine

基　　金：河南省科技攻关项目 ;编号 0 3110 4 4 90 0

摘　　要：目的 :验证火麻仁油是否可通过其润下作用而抗衰老。方法 :用火麻仁油对复方地芬诺脂致便秘模型小鼠进行实验 ,用药共 4 0d ,设空白对照组、阳性对照组、火麻仁油大、小剂量组。结果 :表明火麻仁油能显著降低复方地芬诺脂致便秘模型小鼠血清及脑组织升高的NO水平 ,能显著增加模型组小鼠胸腺厚度及皮质淋巴细胞数 (P <0 .0 1)。结论 :火麻仁油可降低机体的NO及对免疫系统的影响而延缓衰老。Objective: to verify whether Oil of Fructus Cannabis has the effect of anti-senility through its lubrication. Method: make tests on the mice in constipation caused by Compound Di Fen Nuo Zhi for 40days, compared with blank control group, a group given smaller dose of Oil of Fructus Cannabis and a group given larger dose of Oil of Fructus Cannabis. Result: facts have shown that Oil of Fructus Cannabis has the effect of lowering the degree of the sera, brains’ NO and thymus histology of the mice in constipation caused by Compound Di Fen Nuo Zhi. And it can increase the thickness of thymus and cortical lymphocyte of model mice (P<0.01). Conclusion: Oil of Fructus Cannabis can lower the effect of body’s NO on the immune system to postpone senility.

关 键 词：复方地芬诺脂 便秘模型 一氧化氮 火麻仁油 抗衰老 

分 类 号：R285.5[医药卫生—中药学]