Asymmetric Hydroformylation of Olefins Catalyzed by a Chiral Diphosphite-Rhodium Complex  

作　　者：鄢明 黎星术 陈新滋 

机构地区：[1]Department of Chemistry and Chemical Engineering, Suzhou University, Suzhou, Jiangsu 215006, China [2]Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery & Synthesis, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China

出　　处：《Chinese Journal of Chemistry》2004年第2期203-206,共4页中国化学（英文版）

基　　金：Project supported by the Suzhou University and the Hong Kong Polytechnic University ASD Fund and University Grants Committee Area of Excel-lence Scheme in Hong Kong (AoE P/10-01).

摘　　要：A C2-symmetrical aryl diphosphite derived from chiral binaphthol was prepared and its rhodium complex was used as catalysts in the asymmetric hydroformylation of olefins. High catalytic activity and good regioselectivity were observed. Up to 31.2% ee and 38.1% ee were achieved for the hydroformylation of 4-fluoro-styrene and vinyl acetate respectively. The influences of ligand-to-metal ratio, reaction temperature and the pressure of syn-gas on the enantioselectivity and regioselectivity were also studied.A C2-symmetrical aryl diphosphite derived from chiral binaphthol was prepared and its rhodium complex was used as catalysts in the asymmetric hydroformylation of olefins. High catalytic activity and good regioselectivity were observed. Up to 31.2% ee and 38.1% ee were achieved for the hydroformylation of 4-fluoro-styrene and vinyl acetate respectively. The influences of ligand-to-metal ratio, reaction temperature and the pressure of syn-gas on the enantioselectivity and regioselectivity were also studied.

关 键 词：diphosphite chiral ligand asymmetric hydroformylation OLEFIN rhodium complex 

分 类 号：O643.3[理学—物理化学]