药物对美洲大蠊腹神经索阻断作用的电生理学研究  

ELECTROPHYSIOLOGICAL STUDY oF THE BLOCKING EFFECT OF DRUGS ON THE ABDOMINAL NERVE CORD OF PERIPL ANETA AMERICANA

作　　者：熊春生[1] 

机构地区：[1]军事医学科学院微生物流行病研究所,北京100071

出　　处：《医学动物防制》1992年第1期6-9,共4页Journal of Medical Pest Control

摘　　要：用电生理学方法,以美洲大蠊腹神经索作实验标本,测定了杀虫药生物丙烯菊酯、杀鼠药去甲溴杀灵和突触前神经—肌肉传递阻断剂川楝素,对突触传递和神经传导的阻断作用。发现这三个药物均对腹六神经节突触传递有阻断作用。生物丙烯菊酯和去甲溴杀灵对腹神经索巨轴突神经传导也有阻断作用。川楝素则未见对神经传导有明显的阻断作用。The blocking effect of three differant drugs, esbiothrin(insecticidalagent), demethylbromethalin(rodenticide)and toosendanin(presynaptic blocker of neuromuscular transmission), on the abdominal nerve cord of Amerrican cockroach was investigated with electrophysiological method. It was found that the three drugs had a blocking effect on the synaptic transmission of the sixth abdominal ganglia. With the exception of toosendanin, the neural conduction of the giant axon can be blocked too by other two drugs.

关 键 词：生物丙烯菊酯 去甲溴杀灵 川楝素 

分 类 号：R384.9[医药卫生—医学寄生虫学]