葛根素磷脂复合物的红外和紫外光谱分析研究  

The Study on IR and UV Spectral Analysis of Puerarin Phytosomes

作　　者：祝业光 高尔[2] 郝耀礼 王守训[2] 王汝琴[3] 

机构地区：[1]潍坊市药品检验所,山东潍坊261041 [2]潍坊医学院应用药理实验室 [3]潍坊医学院附属医院药剂科

出　　处：《潍坊医学院学报》2003年第5期355-356,I002,共3页Acta Academiae Medicinae Weifang

摘　　要：目的　确定葛根素磷脂复合物的化学光谱特征。方法　用红外分光光度计和紫外分光光度计分别对大豆磷脂、葛根素、葛根素磷脂复合物进行光谱分析。结果　红外光谱分析表明 ,磷脂复合物的光谱为葛根素与磷脂不同光谱的加合 ,紫外光谱分析可见磷脂复合物与葛根素吸收峰均在 2 5 1nm处。结论　红外和紫外光谱证明葛根素与磷脂形成的是磷脂复合物。Objective To determine the chemical spectral character of Puerarin phytosomes.Methods Spectroscopic analysis of phospholipides,Puerarin and Puerarin phytosomes was performed with infrared and ultraviolet spectrophotometers.Results Infrared spectral analysis shows that the spectrum of the Puerarin phytosomes was the combination of the spectrum of Puerarin and phospholipids.Ultraviolet spectral analysis shows that the absorption maxinum of both Puerarin phytosomes and Puerarin was at 251.5nm.Conclusion Infrared and ultraviolet spectroscopic analysis proves that Puerarin and phospholipides compose phytosomes.

关 键 词：葛根素 葛根素磷脂复合物 红外光谱 紫外光谱 

分 类 号：R961[医药卫生—药理学]