二甲氧基羟基苯基荧光酮光度法测药物中的钼  

Spectrophotometric determination of trace molybdenum in medicines withdimethoxyhydroxyphenylflurone(DMHPF)

作　　者：康新平[1] 潘教麦[2] 

机构地区：[1]新疆医科大学药学院,新疆乌鲁木齐830054 [2]华东师范大学化学系,上海200062

出　　处：《化学研究与应用》2004年第1期95-96,共2页Chemical Research and Application

摘　　要：A spectrophotometric method for determination of trace molybdenum with a chromogenic reagent DMHPF was studied.In H2SO4-H3PO4 medium,molybdenum formed an orange-red 1∶2 complex with DMHPF in the presence of Triton X-100,which had absorbance maximum at 526 nm.The apparent molar absorptivity is 1.4×105L·mol-1·cm-1.Beer’ law was obeyed for molybdenum in the range of 0～10μg/25ml.Most of other metal ions do not interfere with the determination.The present method was used to determine trace molybdenum in medicinal tablets with satisfactory results.A spectrophotometric method for determination of trace molybdenum with a chromogenic reagent DMHPF was studied.In H_2SO_4-H_3PO_4 medium,molybdenum formed an orange-red 1∶2 complex with DMHPF in the presence of Triton X-100,which had absorbance maximum at 526 nm.The apparent molar absorptivity is 1.4×10~5L·mol^(-1)·cm^(-1).Beer' law was obeyed for molybdenum in the range of 0～10μg/25ml.Most of other metal ions do not interfere with the determination.The present method was used to determine trace molybdenum in medicinal tablets with satisfactory results.

关 键 词：药物 钼 含量测定 二甲氧基羟基苯基荧光酮 分光光度法 微量元素 

分 类 号：R927.2[医药卫生—药学]