合成光学活性樟脑  

PREPARATION OF OPTICALLY ACTIVE CAMPHOR

作　　者：李允隆[1] 陈庆之[1] 杨国丽[1] 曹舒林[1] 蔡晓军[1] 刘尧权[1] 

机构地区：[1]中国科学院广州化学研究所,广州510650

出　　处：《应用化学》1992年第4期117-119,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金

摘　　要：目前按所谓“四步法”生产的合成樟脑是消旋的。天然樟脑是光学活性的,大多数为右旋体。左旋天然樟脑较为稀少。藤原羲人,松原羲治等曾报道合成光学活性樟脑,其中龙脑脱氢反应是在有机溶剂的存在下进行的,产物的光学纯度为原料的70%左右。Optically active camphor(3) was synthesized in rational yield via dehydrogenation of n-borneol (2a) which was a natural product or obtained via hydration of 2-pinene(1) by one step. The dehydrogenation was carried out in the presence of Zn-laden catalyst, in gasphase,with6ut use of any solvents. The camphor obtained possesses almost the same optical pureness as its starting material-natural n-borneol or 2-pinene.

关 键 词：樟脑 光学活性 脱氢 合成 

分 类 号：O626[理学—有机化学]