平溃散对急性胃溃疡及胃黏膜损伤的保护作用  

Protection of Pingkui Powder from acute gastric ulcer in rats

作　　者：林长征[1] 曹永孝[1] 李长顺[1] 刘静[1] 

机构地区：[1]西安交通大学,陕西西安710061

出　　处：《中成药》2004年第2期128-130,共3页Chinese Traditional Patent Medicine

基　　金：陕西省科技发展计划项目 (2 0 0 1K11-G7)

摘　　要：目的 :研究平溃散 (绞股蓝 ,沙棘等 )对抗急性溃疡的作用。方法 :采用组织胺和消炎痛法建立大鼠实验模型 ,测量溃疡面积和胃黏液的量。结果 :平溃散对组胺引起的急性溃疡有一定的抑制作用 ,对消炎痛引起的胃黏膜分泌的减少有一定的抑制作用。结论 :平溃散具有抗溃疡、保护胃黏膜的作用。AIM: To study the action of Pingkui Powder (Herba Gynostemmatis Pentaphylli, Fructus Hippophae, etc.) on the experimental acute gastric ulcer and its influence on gastric mucosa injury in rats. METHODS: The experimental models were established by means of histamine and indomethacin, area of ulcer was measured and quantity of gastric mucosa secretion of rats was analyzed. RESULTS: Pingkui Powder could reduce areas of ulcers, promote the gastric mucosa secretion. CONCLUSION: Pingkui Powder can improve the healing of acute ulcer and promote gastric mucosa secretion.

关 键 词：平溃散 胃溃疡 胃黏膜损伤 组胺 

分 类 号：R285.6[医药卫生—中药学]