缺血性心脏病Q-T间期变异昼夜规律与心率变异性的关系  

Relation between day-night rhythms of Q-T variability and heart rate variability in ischemic heart disease.

作　　者：嵇平[1] 

机构地区：[1]东南大学附属江北人民医院功能科,南京市210048

出　　处：《心电学杂志》2004年第1期6-7,共2页Journal of Electrocardiology(China)

摘　　要：目的研究缺血性心脏病患者Q-T间期变异昼夜规律及与心率变异性的关系。方法分析50例缺血性心脏病患者和58例对照组的24h动态心电图中06∶01～22∶00和22∶01～06∶00的Q-T间期、Q-T间期变异、SDNN、Q-T/HR斜率的变化及昼夜规律。结果对照组和缺血组心率、Q-T间期、Q-T间期变异、SDNN、Q-T/HR斜率均呈明显的昼夜规律,缺血组与对照组昼夜心率、Q-T间期无明显差异(P>0.05);但SDNN明显减小、Q-T间期变异增大、Q-T/HR斜率也增大(P<0.05)。结论Q-T间期变异、Q-T/HR斜率能反映心室水平的自主神经调节及心室肌本身的状态,对预测室性心律失常及猝死的发生具有重要的价值和临床意义。Objective To evaluate relation between day-night rhythms of QTV and HRV in ischemic heart disease patients. Methods 50 patients and 58 healthy subjects were examined by 24 hours Holter monitoring to study change and day-night rhythms of QT interval?QTV?SDNN?QT/HRslope during 06:01～22:00 and 22:01～06:00. Results HR?QT interval?QTV?SDNN? QT/HRslope shewed day- night rhythms in two groups. HR and QT interval were of little difference between two groups (P>0.05). Patients with ischemic heart disease had significant lower SDNN and greater OTV? QT/HRslope than healthy subjects(P<0.05). Conclusion QTV?QT/HRslope can better reflect automatic nervous activity at level of ventricular and damages of ventricular muscle. It is important value for prognosticate to ventricular arrhythmia and sudden death.

关 键 词：缺血性心脏病 Q-T间期变异 昼夜规律 心率变异性 心电图 诊断 

分 类 号：R541.7[医药卫生—心血管疾病]