12味中药及其复方对大肠杆菌的体外抑菌试验  

Bacteriostatic Experiment of Twelve Species of Chinese Medicines and Its Compounds Against Escherichia Coli

作　　者：胥洪灿[1] 宋友文[1] 

机构地区：[1]西南农业大学荣昌校区,重庆荣昌402460

出　　处：《四川畜牧兽医》2004年第3期24-25,28,共3页Sichuan Animal & Veterinary Sciences

摘　　要：采用体外抑菌试验方法,观察十二味中药及几个复方对大肠杆菌K88和溶血性大肠杆菌的体外抑菌试验。试验结果:12味中药中,有9味中药(冰片、狼毒、白砒、斑蝥、重楼、红芽大戟、白花蛇舌草、黄连、三棵针)均对大肠杆菌K88有抑制作用,其中11味中药(冰片、狼毒、紫贝天葵、白砒、斑蝥、重楼、樟脑、红芽大戟、白花蛇舌草、黄连、三棵针)均对溶血性大肠杆菌有抑制作用。组成的1～7个复方,均对大肠杆菌K88和溶血性大肠杆菌有抑制作用。复方5与恩诺沙星(1‰)时大肠杆菌K88的抑菌作用比较,前者优于后者,其差异显著(P<0.05);复方5与恩诺沙星(1‰)对溶血性大肠杆菌的抑菌作用比较,前者优于后者,其差异极显著(P<0.01),黄连与恩诺沙星相配有协同作用。Bacteriostatic experiment of twelve species of Chinese medicines and its compounds against escherichia coli K88 and hemoclatic escherichia coli had been made.The result showed that nine species of Chinese medicines had shown bacteriostasis against escherichia coli K88 and eleven species against hemoclastic escherichia coli. All compounds had shown bacteriostasis against escherichia coli Kgg and hemoclastic escherichia coli.The bacteriostatic effect of compuond 5 was superior to enrofloxacin's(1‰) against escherichia coli K88 (P<0.05), and the bacteriostatic effect of compound 5 was superior to enrofloxacin's (1‰) against hemoclastic escherichia coli (P<0.01 ).There was synergism between coptis root and enrofloxacin.

关 键 词：中药 复方制剂 大肠杆菌 体外抑菌试验 

分 类 号：S853.7[农业科学—临床兽医学]