密闭液性环境干燥环境下供皮区创面愈合的比较研究  

COMPARATIVE RESEARCH OF THE DONOR SITE WOUND HEALING IN OCCLUSIVE AND DRY ENVIRONMENTS

作　　者：张洁[1] 牛星焘[1] 李东[1] 

机构地区：[1]北京大学第三医院成形外科,北京100083

出　　处：《中国修复重建外科杂志》2004年第2期152-155,共4页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的　比较研究密闭液性环境和干燥环境下供皮区创面的愈合过程。　方法　 1996年 7月～ 1997年3月以 13例成人断层供皮区创面为研究对象 ,其中男 9例 ,女 4例 ,年龄 2 0～ 5 0岁 ,创面面积 (10 0～ 4 0 0 ) cm2 ,取皮深度中厚 ,约 0 .4 4 mm。同一个创面分为实验组 (密闭液性环境 )和对照组 (干燥环境 ) ,采用自身对照法。应用大体、组织学及电镜观察等方法进行观察。　结果　密闭液性环境下创面愈合较快 ,创面组织中成纤维细胞较早活跃、且持续时间较长 ,再血管化和再上皮化均较早和较快发生。　结论　密闭液性环境下创面愈合较快 ,与组织修复细胞较为活跃、再血管化和再上皮化较快发生有关。Objective To compare and research the process of wound healing in occlusive moist environment and dry environment on the skin donor site. Methods The wound healing of adult skin donor site was studied by clinical observation, histological and electromicroscopical examinations on the operative day and the 1st, 2nd, 3rd, 4th, 7th days postoperatively, each skin donor site was divided into two parts: occlusive environment and dry environment. Results The wounds of occlusive moist environment healed faster than those of dry environment; the fibroblasts were more active and activated earlier, revascularization and re-epithelialization happened earlier and more quickly. Conclusion In occlusive environment, more active fibroblasts can accelerate granulation growth; quicker regenerative capillaries bring more nourishment; quicker re-epithelialization accelerates the wound healing.

关 键 词：密闭液性环境 干燥环境 供皮区 创面愈合 比较 组织学 电镜 

分 类 号：R622[医药卫生—整形外科]