持续性植物状态猫脑脊液中多巴胺变化实验研究  

Experimental study on the changes of dopamine in cerebrospinal fluid in the cats with persistent vegetative state

作　　者：肖华[1] 徐如祥[1] 李金彩[2] 

机构地区：[1]第一军医大学珠江医院,广东广州510282 [2]新乡医学院第三附属医院神经内科,河南新乡453003

出　　处：《中华神经外科疾病研究杂志》2003年第2期149-151,共3页Chinese Journal of Neurosurgical Disease Research

基　　金：全军医学科研"十五"计划基金资助项目 (0 1Z0 54);2 0 0 1河南省高校杰出科研人才创新工程基金资助项目(2 0 0 1KYCX0 0 3)

摘　　要：目的　探讨持续性植物状态猫脑脊液中多巴胺的变化及其意义。方法　用高效液相色谱测定持续性植物状态猫脑脊液中多巴胺含量 ,并与正常对照组对比。结果　持续性植物状态猫的脑脊液中多巴胺含量显著降低。Objective To study the changes of dopamine in cerebrospinal fluid in the cats with persistent vegetative state (PVS). Methods To measure the levels of dopamine in cerebrospinal fluid by high performance liquid chromatography with electrical chemical detect(HPLC ECD) in the cats with PVS and compare the values with the controls. Results The level of dopamine in cerebrospinal fluid in the cats with PVS was obviously lower than that of control groups.Conclusion One of possible pathogenetic causes of PVS in cats is the decrease of dopamine .

关 键 词：持续性植物状态 脑脊液 多巴胺 实验研究 

分 类 号：R651.15[医药卫生—外科学]