HGF应用于鼓膜修补术的临床研究  

The clinical study of HGF in myringoplasty

作　　者：蒲一平[1] 吴家廉[1] 骆文龙[1] 周翠英[1] 

机构地区：[1]重庆医科大学第二临床学院耳鼻咽喉科,重庆400010

出　　处：《重庆医科大学学报》2003年第3期334-335,357,共3页Journal of Chongqing Medical University

摘　　要：目的 :研究HGF在鼓膜修补术中促进鼓膜愈合的作用。方法 :对 5 9例长期不愈的鼓膜穿孔患者 ,于鼓膜修补术中应用肝细胞生长因子 (HGF)。结果 :经临床观察 ,用HGF后鼓膜愈合好 ,愈合时间平均约为 9天 ,未见不良反应。结论 :HGF局部应用具有促进鼓膜穿孔愈合的作用。Objective:To investigate the role of HGF in myringoplasty.Methods:Fifty-nine cases of chronic tympanic membrane(TM) perforation were treated with hepatocyte growth fator(HGF) in myringoplasty.Results:According to the clinical observation,the average healing time after myringoplasty was 9 days.Side effect was not observed.Conclusion:The result showed that HGF could improve the healing of TM perforation.

关 键 词：鼓膜穿孔 鼓膜穿孔愈合 鼓膜修补术 细胞因子 肝细胞生长因子 

分 类 号：R764.92[医药卫生—耳鼻咽喉科]