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机构地区:[1]南京军区南京总医院妇产科,江苏南京,210002
出 处:《医学研究生学报》2003年第5期376-378,共3页Journal of Medical Postgraduates
摘 要:多囊性卵巢综合征 (PCOS)是具有遗传倾向、临床表现多样化的疾病 ,以月经稀发或闭经、无排卵或不孕症、多毛或黑棘皮症等临床表现为特征。现虽认为胰岛素抵抗可能是一个重要的发病因素 ,但总的来说PCOS的病因尚不明确 ,所以目前的治疗主要是对症处理 ,包括调整生活方式、周期性使用孕激素和抗雄激素药物。胰岛素增敏剂可能给PCOS的治疗带来新的希望。以后的研究方向为阐明其发病机制 。The polycystic ovray syndrome(PCOS) is a heterogeneous condition with genetic predisposition. It is characterized by a myriad of symptoms including oligomenorrhea or amenorrhea,anovulation or infertility,hirsutism or acne. Insulin resistance appears to be an important factor in PCOS though the lack of an etiology has led to symptom oriented therapy which includes lifestyle modification,the use of cyclical progestagens and antiandrogens. Therapeutic approaches to PCOS remain an ongoing source of debate. Insulin sensitizing agents may bring new hope in therapy. Future research is aimed at shedding light on the pathophysiology so as to optimize treatment of women with PCOS.
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