1997～2001年间31个不同传染性法氏囊病病毒分离株的致病性研究  

Comparisons on pathogenicity of 31 field strains of infections bursal disease viruses isolated in China during 1997～2001

作　　者：孙淑红[1] 崔治中[1] 金文杰[2] 王增福[1] 张纪元[1] 

机构地区：[1]山东农业大学动物科技学院,山东泰安281018 [2]扬州大学畜牧兽医学院,江苏扬州225009

出　　处：《中国预防兽医学报》2004年第2期121-126,共6页Chinese Journal of Preventive Veterinary Medicine

基　　金：国家自然科学基金重大项目(#39893290)的一部分

摘　　要：对1997～2001年间从不同地区收集到的31个鸡传染性法氏囊病病毒(IBDV)野毒株分别人工感染3～7周龄SPF鸡,以比较和确定它们的致病性。比较试验表明,不同毒株间的毒力差异很大,人工感染鸡的年龄也对病毒的致死率有很大影响,4周龄SPF鸡最易感。致病性最强的GX8/99不仅有较明显的易感年龄范围,而且可稳定地引起高达70%～92%的死亡率,是一株真正的超强毒。而人工接种YN2/99株的SPF鸡的死亡率几乎为零。其余毒株对SPF鸡的致死率则介于6%～77%间,但是所有毒株都能造成法氏囊和胸腺的显著萎缩。本研究还表明,我国近几年流行的IBDV大多数毒株的毒力介于典型的超强毒和标准毒之间。Pathogenicity of 31 field strains of infections bursal diseas virues(IBDV)isolated during 1997～2001 in China was compared in SPF chickens of diferent ages.The results indicated that the mortality induced by different strains varied very much.The mortality was also influenced by the age of chickens when infected.Chickens at 4 weeks of age were the most sensitive.Among 31 strains,GX-8/99 was the most virulent,which could cause as high mortality as 70 %～94 % in the relatively wide ranges of ages.In contrac to GX-8/99,anothor strain YN2/99 caused no mortality.The left strains induced mortality in the ranges of 6 %～77 %.However,all strains could cause severe atrophy of the busra and thymuses.The results also indicated that the virulence of the most IBDV field collected in recent years was between the typical very virulent and standard virulent strains

关 键 词：鸡传染性法氏囊病毒 致病性 死亡率 

分 类 号：S852.65[农业科学—基础兽医学]