非线性主成分回归分光光度法同时测定复方制剂中两组分的含量  

Simultaneous determination of benzoic acid and salicyic acid in their mixture by non-linear PCR spectrophotometry

作　　者：周彤[1] 钟家跃[1] 袁萍[1] 

机构地区：[1]江西医学院,南昌330006

出　　处：《分析试验室》2004年第2期57-59,共3页Chinese Journal of Analysis Laboratory

基　　金：江西省自然科学基金资助项目(010006)

摘　　要：构造多组分体系的非线性模型,并用主成分回归法来解析,建立了同时测定两组分的非线性主成分回归分光光度法,方法用于复方苯甲酸制剂中苯甲酸和水杨酸含量的测定,结果优于线性主成分回归分光光度法。A nonlinear model of multiple components systems was developed and ultraviolet spectra data were analyzed by principal component regression. A method for the simultaneous determination of two components with nonlinear principal component regression was established. The method was applied to the simultaneous determination of benzoic acid and salicylic acid in their mixture. The results by nonlinear PCR method were better than those by linear PCR method.

关 键 词：非线性主成分回归法 分光光度法 同时测定 复方制剂 含量测定 苯甲酸 水杨酸 三酸散 

分 类 号：R927.2[医药卫生—药学]