止泻胶囊中岩白菜素的HPLC测定  

Determination of Bergenin in Zhixie Capsules by HPLC

作　　者：李忠琼[1] 张雯洁[1] 马昕[1] 杨雄 

机构地区：[1]云南省药品检验所,云南昆明650011 [2]云南楚雄雁塔药业有限公司,云南楚雄650000

出　　处：《中国医药工业杂志》2004年第3期170-171,共2页Chinese Journal of Pharmaceuticals

摘　　要：建立了止泻胶囊中岩白菜素的HPLC测定方法。采用超声提取岩白菜素,采用ODS C18柱,甲醇-水(20∶80)为流动相,检测波长275nm,在0.2～2.8mg进样量范围内线性关系良好(r=0.9999),平均加样回收率为98.4%,RSD为1.3%。A HPLC method for determination of bergenin in Zhixie capsules was established. Bergenin wasextracted by methanol and ultrasonic agitation. An ODS C18 column was used with the mobile phase of methanol-water(20∶80), at the detection wavelength of 275nm. The calibration curve was linear in the range of 0.2～ 2.8mg (r=0.9999).The average recovery was 98.4% (RSD 1.3%).

关 键 词：止泻胶囊 岩白菜素 高效液相色谱 测定 

分 类 号：TQ460.72[医药卫生—药物分析学] O657.72[化学工程—制药化工]