溶胶-凝胶法制备生物活性玻璃陶瓷的研究  

STUDY ON PREPARATION OF BIOACTIVE GLASS-CERAMICS BY SOL - GEL METHOD

作　　者：杨为中[1] 周大利[1] 尹光福[1] 陈槐卿[2] 郑昌琼[1] 

机构地区：[1]四川大学材料科学与工程学院无机非金属材料系,成都610065 [2]四川大学生物医学工程研究室,成都610041

出　　处：《硅酸盐学报》2004年第2期171-176,共6页Journal of The Chinese Ceramic Society

基　　金：国家863高技术计划(2002AA326080);教育部优秀青年教师基金(2002123)资助项目

摘　　要：采用溶胶-凝胶法制备前驱体粉体,经高温煅烧制备了名义化学组成为MgO4.6,CaO44.9,SiO2 34.2,P2O516.3,CaF20.5(质量分数)的磷灰石-硅灰石生物活性玻璃陶瓷。用造孔工艺制备了其多孔型材料。通过实验观察、差热和热重分析,体积密度和气孔率的测量,粒度测试、X射线衍射分析,扫描电镜观测,FTIR转换红外光谱分析等方法,研究了玻璃陶瓷前驱体粉末的溶胶-凝胶制备工艺条件,玻璃陶瓷的烧结工艺条件;分析了材料的晶相结构和显微结构。实验结果表明:溶胶-凝胶法可制备出微细的非晶态前驱体粉末,经烧结后玻璃陶瓷主晶相为磷灰石及β-硅灰石。造孔后,多孔型材料具有良好的贯通孔隙结构:微观孔隙约2～3 μm,宏观孔隙约300～400μm。鉴于其晶相组成及良好的微观结构,通过新型溶胶-凝胶工艺开发的生物活性玻璃陶瓷材料可望被用于骨修复材料及骨组织工程支架材料。A new type of apatite-wollastonite (AW)bioactive glass-ceramics with nominal chemical composition of MgO 4.6, CaO 44.9, SiO2 34.2, P2O5 16.3, CaF2 0.5 (in mass fraction) was prepared by sintering precursor powders derived from sol-gel process. The porous ceramics was developed by pore-forming method. The preparation process of precursor powders by sol-gel method, the sintering process condition of glass-ceramics, the crystalline structure and the microstructure of the materials were studied by means of DTA, TG, XRD, SEM, FTIR and so on. Results show that superfine precursor powders with noncrystalline structure can be prepared from sol-gel process. The main crystalline phases of the sintered glass-ceramics are apatite and β-wollastonite. After pore-forming, the porous material has interconnected pore structure with micro-pore of about 2-3 μm and macro-pore of about 300-400 μm. It is expected that the AW glass-ceramics prepared by newly developed sol-gel method will be a bone grafting material and carrier material for bone tissue engineering due to its excellent crystalline structure and micro-structure.

关 键 词：溶胶-凝胶 玻璃陶瓷 磷灰石 硅灰石 生物活性 

分 类 号：TQ174.59[化学工程—陶瓷工业]