不稳定型心绞痛介入治疗疗效观察  

Observation of the therapeutic effects in treating unstable stenocardia with drug and interventional methods

作　　者：杨绍祥[1] 陈玉国[2] 

机构地区：[1]山东大学医学院,山东济南250013 [2]山东大学齐鲁医院,山东济南250013

出　　处：《实用医药杂志》2003年第5期321-322,共2页Practical Journal of Medicine & Pharmacy

摘　　要：目的比较经皮冠脉介入治疗(Percutaneouscoronaryintervention,PCI)和药物治疗不稳定型心绞痛(Unstableanginapectoris,UAP)的近期临床疗效。方法112例不稳定型心绞痛病人分两组,57例行PCI,55例给予阿司匹林、低分子肝素、硝酸酯类及β受体阻滞剂等治疗。分别观察两组病人临床症状和心电图变化以及6个月主要心血管事件的发生率。结果PCI组总有效率及显效率均显著高于药物治疗组(P<0.05),尤其是中高危病人,其主要心血管事件的发生率低于药物治疗组(P<0.01)。结论不稳定型心绞痛特别是中高危病人介入治疗优于药物治疗。Objective To Compare the clinical effects of treating unstable angina with drugs and interventional methods.Methods The96patients with unstable angina pectoris were divided into two groups,one group treated with PCI(including percutaneous transluminal coronary angioplasty and stenting),another with traditional drugs alone including Aspirin,low-molecule-weight heparin,nitrtates,β-blockers and so on.The in-hospital changes of clinical symptoms and electrocardiograph(ECG)and the major cardiac adverse events at6months were observed.Results The total effective rate and the distinctly improving rate of interventional group were much higher than that of the drug-treated group,particularly in patients at moderate and high -risk.And the former was associated with lower cardiac events compared with the latter.Conclusion The therapeutic effect of interventional treatment is better than that of the drugtreatment,especially in patients with UAP at moderate and high-risk.

关 键 词：不稳定型心绞痛 介入治疗 药物治疗 

分 类 号：R541.4[医药卫生—心血管疾病]