蛹虫草菌粉胶囊治疗慢性支气管炎510例  

Efficacy of Cordyceps militaris capsules in treatment of chronic bronchitis

作　　者：蔡鸿彦[1] 刘志成[1] 逄建伟[1] 刘嵋松[1] 王晓岩[1] 

机构地区：[1]吉林省中医中药研究院国家药品临床研究基地,长春130021

出　　处：《中国新药杂志》2004年第2期171-174,共4页Chinese Journal of New Drugs

摘　　要：目的:观察蛹虫草菌粉胶囊治疗慢性支气管炎迁延期的疗效与安全性。方法:本试验为Ⅲ期临床试验,随机选取510例慢性支气管炎迁延期的患者,从咳嗽、咳痰、喘息、肺部哮鸣音、肺功能、肺部X线征象等方面观察治疗前后的变化,进行统计学处理,并考察其安全性。结果:治疗后患者的慢支症状及体征均有显著改善(P<0.05);治疗慢性支气管炎迁延期的总有效率为88.04％,显效率为57.26％。结论:蛹虫草菌粉胶囊确为治疗慢性支气管炎迁延期属肺气虚、肾阳虚证候的安全有效的药物。Objective:To observe the efficacy of Cordyceps militaris capsules in treatment of chronic bronchitis. Methods: The phase Ⅲ clinical trial was conducted in 510 patients with chronic bronchitis. The symptoms of cough,sputum, wheeze and wheezing rale,as well as lung function,chest X ray examination, and others were recorded before and after treatment with Cordyceps militaris capsules. Data obtained were statistically analyzed and the safety of the drug was also observed. Results: The symptom in patients with chronic bronchitis was significantly improved after treatment with Cordyceps militaris capsules (P < 0. 05) with an effective rate of 88. 04% . Conclusion: Cordyceps militaris capsules is an effective agent for treatment of chronic bronchitis.

关 键 词：蛹虫草菌粉胶囊 慢性支气管炎 Ⅲ期临床试验 

分 类 号：R285.6[医药卫生—中药学] R289.5[医药卫生—中医学]