硅胶整体柱的制备及制备条件对整体柱的影响  

Preparation of Monolithic Silica Column and the Effect of Preparative Conditions on Monolithic Column

作　　者：高文惠[1] 杨静[1] 杨更亮[1] 胡汉芳[1] 刘海燕[1] 

机构地区：[1]河北大学化学与环境科学学院

出　　处：《化学通报》2004年第3期214-217,共4页Chemistry

基　　金：国家自然科学基金 (2 0 0 75 0 0 5 );河北省自然科学基金 (2 0 0 0 77);科技部基金资助项目

摘　　要：研究了硅胶整体柱的制备工艺及温度、p H对凝胶化过程的影响 ,探讨了不同的四甲氧基硅烷 /聚乙二醇比例、不同制孔剂浓度对柱结构的影响 ,以及不同焙烧温度和酸活化处理方法对柱体 Si-OH含量和线性收缩率的影响 ,由此确定最佳制备条件。结果表明 ,采用改进的溶胶 -凝胶工艺制备的硅胶整体柱 ,无开裂变形现象 ;不同制备条件 ,可以产生具有不同微米级鞍形骨架、微米级大孔和纳米级中孔的整体柱 。In this paper a new approach of preparing monolithic silica column was presented. The effect of pH value and temperature of water-bath in the process of gelation were investigated. The influence of different TMOS/PEG ratio and concentrations of porogenic diluent on monolithic silica column and the change of Si-OH content of monolithic column with roasting temperature were also discussed. The result shows that by adopting the improved sol-gel technology, the monolithic silica column do not crack and deform, and the columns possess both continuous through-pore and silica skeleton with appropriate open mesopore size in different preparation conditions, which can meet the needs of separation and analysis of different-molecular-mass solutes.

关 键 词：硅胶整体柱 制备 溶胶-凝胶工艺 色谱柱 色谱分离 水浴温度 pH值 TMOS/PEG比例 制孔剂浓度 焙烧温度 活化条件 

分 类 号：O657.7[理学—分析化学]