An Efficient Synthesis of [1,2,4]Triazolo[3,2-d][1,5]benzoxazepin-2-thiones, a Kind of Novel Tricyclic O,N-Heterocycles  

作　　者：李诤 孟青青 王全瑞 陶凤岗 

机构地区：[1]Department of Chemistry, Fudan University, Shanghai 200433, China

出　　处：《Chinese Journal of Chemistry》2004年第3期290-295,共6页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China (No. 20372015) and the Key Organic Synthesis Laboratory of Jiangsu Province (No. KJS01016).

摘　　要：A series of novel tricyclic O,N-heterocycles, [1,2,4]triazolo[3,2-d][1,5]benzoxazepin-2-thiones 7 were achieved via acid-induced ring closure of the geminal arylazo isothiocyanate compounds 5 which were derived from substituted chroman-4-ones, followed by feasible ring expansion with simultaneous insertion of the nitrogen atom into the carbon skeleton. The X-ray crystal structure of 7d was also described.A series of novel tricyclic O,N-heterocycles, [1,2,4]triazolo[3,2-d][1,5]benzoxazepin-2-thiones 7 were achieved via acid-induced ring closure of the geminal arylazo isothiocyanate compounds 5 which were derived from substituted chroman-4-ones, followed by feasible ring expansion with simultaneous insertion of the nitrogen atom into the carbon skeleton. The X-ray crystal structure of 7d was also described.

关 键 词：geminal arylazo isothiocyanate ring closure REARRANGEMENT [1 2 4]triazolo[3 2-d][1 5]benzoxazepin-2-thiones 

分 类 号：O621[理学—有机化学]