联合测定血清肝功能酶学在病毒性乙型肝炎诊断中的意义  

DIAGNOSTIC SIGNIFICANCE OF COMBINED SERUM MULTIFARIOUS ENZYMES DETECTION IN PATIENTS WITH HEPATITIS B

作　　者：宗敏[1] 司端勤 朱维林[1] 

机构地区：[1]山东省济宁市传染病医院,272031

出　　处：《青海医药杂志》2004年第1期11-12,共2页Qinghai Medical Journal

摘　　要：目的 :探讨联合测定多种血清肝功能酶对病毒性乙型肝炎诊断的临床意义。方法 :用速率法测定 2 0 4例不同临床类型的病毒性乙型肝炎患者血清中丙氨酸氨基转移酶 (ALT)、天门冬氨酸氨基转移酶 (AST)、线粒体天门冬氨酸氨基转移酶 (m -AST)、碱性磷酸酶 (ALP)、γ -谷氨酰转肽酶(γ -GGT) ,并进行比较。结果 :急性肝炎患者血清中的ALT、AST、m -AST、ALP、γ -GGT水平显著高于轻、中度慢性乙型肝炎 (P <0 .0 1) ,低于重度慢性肝炎 (P <0 .0 1)。结论 :联合测定血清肝功能酶学有助于乙型肝炎的临床分型和预后。Objective:To study the clinical significance of combined detection of serum multifarious enzymes on diagnosis of patients with hepatitis B.Methods: The level of serum ALT, AST, m-AST, ALP and GGT were measured by speed method in 204 patients with different clinical types hepatitis B. The results were compared and analyzed.Results:Compared to the mild and moderate chronic hepatitis B, the level of serum ALT, AST,m-AST,ALP and GGT in patients with acute hepatitis were apparently higher (P<0.01), but lower than that in the serious chronic hepatitis (P<0.01). Conclusion: Combined detection of serum multifarious enzymes is helpful for clinical typing diagnosis and prognosis assessment of hepatitis B.

关 键 词：血清酶学 肝功能 病毒性乙型肝炎 速率法 临床分型 肝纤维化 

分 类 号：R512.62[医药卫生—内科学]