壳聚糖修饰铂电极半微分伏安法测定微量碘  

SEMI-DIFFERENTIAL VOLTAMMETRIC DETERMINATION OF TRACE AMOUNTS OF IODIDE WITH CHITOSAN MODIFIED PLATINUM ELECTRODE

作　　者：刘伟利[1] 吴庆生[1] 丁亚平[2] 

机构地区：[1]同济大学化学系 [2]上海大学化学系,上海200436

出　　处：《理化检验（化学分册）》2004年第3期145-147,共3页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家自然科学基金(No:20175013);上海市高校科技发展基金(01A17)资助项目

摘　　要：将壳聚糖修饰到铂盘电极上,采取半微分伏安法测定微量碘。用0.20mol·L-1NaH2PO4 Na2HPO4(pH6.0)缓冲体系,在0.20～0.65V间以10mV·s-1的速度扫描,碘离子浓度在0.80～25.0μg·ml-1范围内与氧化峰电流呈线性关系(r=0.9996),检出限达0 20μg·ml-1。修饰电极在4.0μg·ml-1KI溶液中,11次测得峰电流的相对标准偏差为3.3%。将该修饰电极用于华素片中微量碘的测定,与间接火焰原子吸收光谱法相比,相对误差在5%以内。In a buffer solution of 0.20mol·L^(-1) NaH_2PO_4-Na_2HPO_4 (PBS, pH 6.0), and scanning from 020V to 0.65V at a rate of 10mV·s^(-1), good linearity is kept between the oxidation peak current (i_p) and the concentration of I^- ion in the range from 0.80 to 25.0μg per ml of solution. The correlation coefficient of the linear regression equation is 0.9996. The detection limit is 0.20μg·ml^(-1). The RSD (n=11) found at the concentration level of 4.0μg of iodide per ml, is 3.3%. This method has been applied to the determination of iodide in cydiodine tablets, and consistent results were obtained as compared with the FAAS method, giving a relative deviation of about 5%. The average recovery of this method obtained by the standard addition method is 93.2%.

关 键 词：壳聚糖 化学修饰铂电极 半微分伏安法 碘 微量分析 含量测定 华素片 药物 

分 类 号：R927.2[医药卫生—药学]