水竹草抗肿瘤成分的研究  

Study on Antineoplastic Components of Zebrina Pendula Schnizl

作　　者：樊效琪 徐亚铭 刘星堦 

机构地区：[1]上海医科大学妇产科医院药剂科,200011 [2]上海医科大学天然药化教研室

出　　处：《中成药》1992年第2期34-35,共2页Chinese Traditional Patent Medicine

摘　　要：自鸭跖草科植物水竹草(Zebrina pendula Schnizl)的全草中分得2个甾醇,经鉴定为β-谷甾醇和3β,5α,6β三羟基豆甾烷及琥珀酸,并经小鼠腹水型180肉瘤的抗癌试验,其抑瘤率分别为琥珀酸43％(160mg/kg);β-谷甾醇91％(100mg/kg);3β,5α,6β三羟基豆甾烷98％(100mg/kg),并发现后者剂量增加时无毒性。Three components have been isolated from Zebrina pendula Schnizl and identified as β-sitosterol, 3β, 5α, 6β-trihydroxy stigmast and succinic acid. As a result the anti-tumor rate were 43% (160mg/kg)for succinicacid, 91% (100mg/kg) for β-sitosterol and 98%(100mg/kg) for 3β, 5α, 6β-trihydroxystigmast, respectively, after anti-cancer test of ascites type-180 sarcoma of mice. It was found that the last hadn't toxicity when its dose was increased.

关 键 词：水竹草 肿瘤 抗肿瘤作用 

分 类 号：R273[医药卫生—中西医结合]