2型糖尿病患者微血管病变与血糖控制的相关性  

Correlation between microvascular lesion and plasma glucose control in type 2 diabetic patients

作　　者：张军[1] 雷闽湘[1] 刘泽灏[1] 陈卓雄[1] 王爱民[1] 

机构地区：[1]中南大学湘雅医院内分泌科,湖南省长沙市410008

出　　处：《中国临床康复》2004年第9期1688-1689,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨血糖控制与糖尿病微血管病变之间的关系,及适合作为评价糖尿病微血管病变风险的血糖控制指标。 方法:回顾性分析837例2型糖尿病患者的临床资料,分析合并微血管病变及无微血管病变患者空腹/餐后2h血糖及糖化血红蛋白水平的差异。 结果:合并微血管病变组的2型糖尿病患者餐后血糖[(15.44±5.31)mmol/L和(14.27±4.53)mmol/L]和糖化血红蛋白[(11.2±1.8)％和(9.8±1.4)％]显著高于对照组,P<0.01。 结论:餐后2h血糖和糖化血红蛋白水平与糖尿病微血管病变呈显著性正相关,是适合作为评价糖尿病微血管病变风险的指标。AIM: To explore the relation between plasma glucose control and diabetic microvascular lesion, and to find out the factors that can evaluate the risk of diabetic microvascular lesion.METHODS: Retrospective analysis was conducted to the clinical data of 837 cases with type 2 diabetes, the differences of fasting plasma glucose (FPG), 2 h postprandial plasma glucose (2 h PG) and hemoglobin A (HbAl c) between patients with or without diabetic microvascular lesion were analyzed.RESULTS: The levels of 2h PG and HbAlc in patients with diabetic microvascular lesion[( 15. 44±5. 31) mmol/L, (11. 2 ±1.8)%] were significantly higher than those in the control group[ (14. 27 ±4. 53) mmol/L, (9. 8 ±1.4)%] (P <0. 01).CONCLUSION: Two hours PG and HbAlc have a significantly positive correlation with the prevalence of diabetic microvascular lesion, and they are more suitable for evaluating the risk of microvascular lesion.

关 键 词：2型糖尿病 微血管病变 血糖控制 相关性 并发症 

分 类 号：R587.2[医药卫生—内分泌] R543[医药卫生—内科学]