冠状动脉血管阻抗估计系统及其临床应用  

A coronary artery impedance estimation system and its clinical application

作　　者：罗忠池[1] 汪源源[1] 王威琪[1] 张良惠[2] 钱菊英[2] 葛均波[2] 

机构地区：[1]复旦大学电子工程系,上海200433 [2]复旦大学附属中山医院心内科,上海200032

出　　处：《声学技术》2004年第1期14-19,共6页Technical Acoustics

基　　金：上海市青年科技启明星跟踪计划资助 ( 0 1QMH14 0 1)

摘　　要：利用PC机和图像、信号采集设备 ,建立冠状动脉血管阻抗的估计系统。该系统从血管内超声和血压检测仪器采集冠状动脉内的超声图像、血流多普勒和血压信号 ,通过提取管腔的截面积曲线和流速信息 ,获取血流量曲线。结合血压曲线 ,计算冠状动脉的等效阻抗。系统对不同程度冠脉狭窄、心肌架桥和微循环障碍病人进行临床应用 ,结果表明 :血管阻抗可以反映血管供血和扩张能力与不同类型、程度病症间的关系 。A PC-based system with video and signal acquisition boards is constructed to estimate coronary artery impedance. Intra-coronary ultrasound images, blood flow Doppler and pressure signals are acquired from intra-vascular ultrasound imaging and blood pressure detection instruments. The blood volume waveform is calculated based on an estimate of the lumen area of the coronary artery and the blood flow velocity waveform. Together with the blood pressure waveform, the coronary artery impedance is obtained. Clinical applications to patients with coronary stenosis, myocardium bridge and microcirculation dysfunction show that the impedance obtained with this system can reflect coronary artery's blood supply and reservation capability under various types and degrees of coronary diseases. The system is applicable to clinical diagnosis.

关 键 词：血管阻抗 冠状动脉 血管内超声 多普勒信号 信号采集设备 超声图像 血压曲线 

分 类 号：R322.12[医药卫生—人体解剖和组织胚胎学] TB559[医药卫生—基础医学]