饮水型氟中毒人群血液某些生化分析  

BIOCHEMICAL STUDY ON BLOOD OF PATIENTS WITH FLUOROSIS FROM DRINKING WATER

作　　者：侯立中[1] 杨春伟[1] 白秀起 焦英军 郭振环 陈志[3] 

机构地区：[1]白求恩医科大学地方病研究所 [2]吉林省地方病办公室 [3]吉林省地方病第一防治研究所

出　　处：《中国地方病防治》1992年第1期13-15,共3页Chinese Journal of Control of Endemic Diseases

基　　金：吉林省科委资助课题

摘　　要：对饮水型氧中毒患者血液酶谱和总蛋白、钙、磷含量的测定结果表明,氟斑牙组儿童血清LDH、α-HBDH活性明显升高,氟骨症组成人LDH、α-HBDH和ALP活性明显升高。对所测9项生化指标进行多元统计分析结果表明,氟斑牙和氟骨症患者与其各健康对照组间的均值向量都差异显著。提示慢性氟中毒引起了机体各测定指标所反映的组织代谢紊乱。Activities of GOT, GPT,CRK,LDH,HBDH and ALP, as well as contents of total protein, calcium and phosphate were examined in the blood of patients with fluorosis from drinking water. The result showed that the activities of LDH,α-HBDH in serum of children with dental fluorosis were significantly increased. The activities of LDH,α-HBDH and ALP in serum of adults skaletal fluorosis were also significantly increased. The differences of mean vectors between both fluorosis groups and healthful groups were remarkable respectively. The result indicates that fluorosis induced metabolic disorder manifested by indexes mentioned above.

关 键 词：氟中毒 乳酸脱氢酶 Α-羟丁酸脱氢酶 

分 类 号：R599.904[医药卫生—内科学]